Therefore, perioperative fluid regimens were traditionally based on a generous replacement of this assumed primary loss, in addition to deficits due to insensible perspiration and fasting. So anyway- here is some peer reviewed information regarding the vascular spaces we deal with рџ™‚ДЇor decades, the вЂthird spaceвЂ™ was looked upon as an actively consuming compartment. ItвЂ™s always cool (and almost glib) to nonchalantly dump out the phrase- вЂњthe pt is thrid spacingвЂќ as an explanation for where our volume might be hiding, or for obvious signs of tissue edema (puffy or swollen faces/hands and feet). I was chatting with the surgeon while he was taking down the IMA, and mentioned that while I was familiar with the concept of вЂњthird spacingвЂќ, I needed to clarify the implied вЂњfirstвЂќ, and вЂњsecondвЂќ spaces. Part of what we do involves some major fluid shifts within the patient as a result of our prime constituents, pharmacological additives administered during the pump run, and the ability of the human body to physiologically compensate for dynamic fluid shifs and variances in Colloidal Osmotic Pressure (COP). вЂњWhile I was familiar with the concept of вЂњthird spacingвЂќ, I needed to clarify the implied вЂњfirstвЂќ, and вЂњsecondвЂќ spaces.вЂќД«ack quite a while ago, I was really into publications, and the academic side of cardiac perfusion and education.

Three body fluid compartments